摘要
目的观察血管性痴呆(VD)患者雌二醇(E2)、睾酮(T)水平的变化,探讨其与VD的关系及中药干预的作用。方法选取本病患者70例,与正常对照组进行E2、T水平比较;并将其随机分成治疗组40例和对照组30例,分别给予中药和西药治疗。结果女性VD患者血清E2水平低于正常组(P<0.05);男性VD患者血清E2、E2/T高于正常组,血清T水平低于正常组(P<0.05)。男、女治疗组治疗前后E2值、E2/T值及男性T值差异有统计学意义(P<0.01)。治疗组有效率85%,对照组有效率60%。结论VD患者存在性激素异常,通过补肾调节性激素是防治VD的有效方法。
Objectives To investigate the relations between serum E2, T level and vascular dementia （VD） and therapy effect of Chinese medicine. Methods Seventy patients were selected and randomly divided into two groups., experimental group, which was treated with Chinese medicine and control group with western medicine. Results There was marked difference in E2 of female patient and E2, E2/T and T of male patient between experimental group and control group （P〈0.05）. There was significant difference in serum E2, E2/T and T of male patient level before and after therapy （P〈0.05）. The total response rate of the experimental group was 85% and that of the control group was 60%. Conclusion There was abnormality of sexual hormone in VD patients and kidney-tonifying method can improve the clinical symptoms and signs of VD.
出处
《中国中医药信息杂志》
CAS
CSCD
2008年第9期14-16,共3页
Chinese Journal of Information on Traditional Chinese Medicine
关键词
血管性痴呆
雌二醇
睾酮
补肾健脾养血活血方
vascular dementia, estradiol
testosterone, kidney-tonifying and spleen-invigorating, blood-nourishing and circulation-activating formula
