摘要
目的探讨尼莫地平控制性降压在脑动脉瘤栓塞术中的可行性。方法选择ASAⅡ～Ⅲ级行脑动脉瘤栓塞术患者55例，均采用静吸复合麻醉，用芬太尼、异丙酚、维库溴安、艾司洛尔诱导，异丙酚持续输注、异氟醚持续吸入，维库溴铵间断推注维持麻醉。待导引管进入靶血管前10rain，静滴0．02％尼莫地平注射液，初速为600～800μg／min，根据血压变化调整用量，使收缩压维持在80～90mmHg。结果55例在滴注尼莫地平后5min内均达到所需低血压水平，停止控制性降压后血压缓慢复升，15～30min内基本恢复到降压前水平，未发生“反跳性”血压升高。结论尼莫地平可有效用于脑动脉瘤栓塞术中的控制性降压。
Objective To investigate the possibility of nimodipine controlled hypotension on embolization operation for cerebral aneurysm. Methods Fifty-five patients （Society of Anesthiologist Ⅱ-Ⅲ） under embolization operation for cerebral aneurysm. All cases were anesthetized by intravenous-inhaltion combined anesthesia, anesthesia was inducted with fentanyl, propofol, vecuronium and esmolol, maintained with continuing intravenous drop of propofol, continuous isoflurane inhaltion and intermittent intravenous injection of vecuronium. Ten minutes before the catheter in target vein, 0. 02% nimodipine was infusion iv wit 600-800μg/min, according to the blood pressure to adjust the dose and maintain SP at the level of 80-90mmHg. Results Five minutes after iv drop nimodipine, all cases reached the necessary hypotension, and the blood pressure was increased slowly after termination of controlled hypotension. 15 - 30 minutes later , BP reached the primary level of hypotension, no rebounded hypertension happened. Conclusion Nimodipine induced controlled blood pressure lowering during embolization operation for cerebral aneurysm is effective .
出处
《中国实用神经疾病杂志》
2008年第9期40-42,共3页
Chinese Journal of Practical Nervous Diseases
关键词
尼莫地平
脑动脉瘤栓塞术
控制性降压
Nimodipine
Embolization operation for cerebral aneurysm
Controlled hypotension
