摘要
以O-马来酸酐化N-邻苯二甲酰化壳聚糖(MPCS)为中间产物,通过γ射线引发,在均相溶液体系制备含有改性壳聚糖-聚丙烯酸的两性凝胶。用红外光谱证实了接枝反应的发生。同时还系统地研究了接枝反应的影响因素,结果表明,接枝率依赖于单体浓度和所用的剂量。通过研究了接枝产物在不同pH值缓冲溶液中溶胀度的变化,结果发现,接枝产物在酸性条件(Ph<7)下溶胀较小,在碱性条件(pH>7)下溶胀度较大。而且还测试了接枝产物在DMF溶剂中的溶胀情况。
Poly （acrylic acid）-modified chitosan amphiphilic gels were prepared via O-maleoyl-N- phthaloyl- chitosan as an intermediate by grafting with poly （acrylic acid）. The reaction was carried out in a homogeneous system by γ-ray irradiation. Evidence of grafting was obtained from FTIR spectroscopy. The effects for grafting reaction were investigated systematically. Results show that the grafting degree depends on monomer concentration and absorbed dose. The swelling behavior of chitosan samples with different grafting degree was studied in different buffers as a function of pH. It can be found that all the samples swollen slightly at low pH but very well at high pH. Moreover, the swelling behavior of chitosan samples in DMF has been evaluated.
出处
《辐射研究与辐射工艺学报》
CAS
CSCD
北大核心
2008年第4期210-214,共5页
Journal of Radiation Research and Radiation Processing
基金
国家自然科学基金(50573073)资助
关键词
壳聚糖
丙烯酸
辐射接枝
PH敏感
Chitosan, Acrylic acid, Radiation induced grafting, pH sensitivity
