摘要
目的:观察小剂量倍他乐克治疗慢性心力衰竭的疗效。方法:将慢性心力衰竭96例随机分为具有可比性的治疗组和对照组,在所有病例均给予强心、利尿和扩血管等常规治疗,治疗组同时加用倍他乐克,自12.5mg/d开始,3～5d后增至25mg/d,以后逐渐增加至50～75mg/d。治疗前后观察两组患者的心率、左室射血分数(LVEF)、左室舒张末内径(LVEDD)及心功能情况。结果:治疗组显效15例,占30.6%;有效22例,占44.9%;无效12例,占24.5%;总有效率为75.5%。对照组显效9例,占20.5%;有效12例,占27.3%;无效23例,占52.3%;总有效率为47.7%。治疗后两组之间的总有效率、心率和心功能差异均有统计学意义(P<0.05)。结论:在接受心力衰竭常规治疗基础上加服小剂量倍他乐克对改善心力衰竭症状具有良好效果。
Objective：To observe the curative effect of small dose Betaloc in the treatment of chronic heart failure. Methods：96 cases of chronic heart failure patients were divided into treatment group andcontrol group. Conventional cardiac,diuresis and vasodilatation treatment were given to both groups,while extra Betaloc treatment was given to the treatment group,starting with giving Betaloc 12.5 mg/d,3～5 days later,increase to 25 mg/d,and progressive increase to 50～75 mg/d; the heart rate,LVEF,LVEDD and heart function of the patients in both groups before and after treatment were observed. Results：The difference in total effective rate,heart rate and heart function between the two groups was of statistical significance. Conclusion：The routine treatment plus small dose Betaloc has good effect in improving the symptoms of heart failure.
出处
《中国医药导报》
CAS
2008年第23期66-67,共2页
China Medical Herald
