摘要
目的比较致动脉粥样硬化指数(AIP)与2型糖尿病(T2DM)和高血压患者冠脉病变程度和斑块性质的相关性,为经皮冠状动脉介入(PCI)手术的选择及再狭窄研究提供参考。方法选择T2DM患者56例,高血压患者39例用64排CT冠脉扫描显示其狭窄程度、斑块性质,病变血管数量及分布,分析和比较T2DM患者和高血压患者中的AIP与冠脉的狭窄程度、病变分布、斑块性质的关系。结果T2DM患者冠脉的狭窄大多数在80%￣95%之间,高血压患者,H-AIP病变多在左冠脉,而T2DM,H-AIP病变较分散,软化斑、混合斑较多,再狭窄严重。而L-AIP高血压病组中,钙化斑、纤维斑较多,再狭窄较少。两组间有统计学差异。结论H-AIP和T2DM患者冠脉狭窄程度较L-AIP和高血压组的患者严重,且病变范围较广,多为软化斑块及混合斑块,再狭窄严重。MCT是一种快速、直观、可动态观察冠脉病变及再狭窄的一种新方法。AIP和MCT的结合可为PCI手术患者的选择和再狭窄的诊断提供方便和证据,尤其是T2DM患者。
Objective To evaluate the correlation between atherogenic index of plasma （AIP） and coronary artery lesions （CAL） in the patients with type 2 diabetes mellitus（T2DM）and hypertension and to provide the reference for selecting the operation of percutaneous coronary intervention （PCI） and studing the restenosis.Methods Ninety-five patients who comprised 56 T2DM and 39 hypertension,whose coronary artery stenosis （CAS） severity,plaque property and involved blood vessel number and distribution were visualized by using 64- detector row CT coronary angiography,and then the correlation between AIP and CAS severity,lesion distribution,plaque property in T2DM patients was analyzed and compared with that in hypertension patients.Results T2DM patients whose CAS mostly ranged from 80 percent to 95 percent.Hypertension patients with high AIP,whose lesions mostly localized in the left coronary arteries,while T2DM patients with high AIP,whose lesions were scattered and the most presented as malacotic plaque and mixed plaque associated with severe restenosis but hypertension patients with low AIP, whose lesions mostly presonted as calcified plaque and fibrous plaque and rarely associated with restenosis so that there was statistic difference between above both groups.Concluslon Compared with hypertension patients with low AIP, T2DM patients with high AIP whose CAS was more severe,the range of lesions was more wide and mostly presented as malacotic plaque and mixed plaque associated with severe restenosis.64-detector row CT coronary angiography is a new means which can quickly,direct and dynamically observe the lesion or restenosis of coronary artery.The integration of AIP and 64-detector row CT can provide the convenience and evidence for selecting the operation of PCI and diagnosing the restenosis,especially,T2DM patients.
出处
《实用医学影像杂志》
2008年第4期259-261,共3页
Journal of Practical Medical Imaging
