摘要
碘是合成甲状腺激素的主要原料之一,适宜的碘摄入水平对维持正常的甲状腺形态和功能具有重要的意义。碘摄入过多可诱发或加重自身免疫性甲状腺疾病(AITD)的发生、进展,这在流行病学调查和动物模型中均得到了证实。建立碘摄入量的安全范围,对AITD的预防具有重要的意义。
Iodine is one of the important materials in thyroid hormone synthesis, and appropriate iodine intake is crucial for maintenance of thyroid morphology and function. Iodine excess tends to induce or aggravate the occurrence and development of autoimmune thyroid diseases (AITD) ,which has been demonstrated by epidemiological investigation and animal models. Therefore, it is important to establish safe or optimal range of iodine intake for AITD prevention.
出处
《医学综述》
2008年第16期2502-2505,共4页
Medical Recapitulate
关键词
碘摄入
自身免疫性甲状腺疾病
流行
机制
Lodine intake
Autoimmune thyroid disease
Prevalence
Mechanism