摘要
目的:观察以全反式维甲酸为主的治疗方案治疗骨髓增生异常综合征(MDS)的临床效果。方法:2001年3月-2007年3月来我院治疗的低危组骨髓增生异常综合征患者68例,随机分为治疗组和对照组。对照组中的低危组给予叶酸、维生素B12和雄激素。治疗组在补充叶酸、维生素B12的治疗基础上加服全反式维甲酸。结果:治疗组的总有效率为75.61%,高于对照组的48.15%,两者之间有统计学意义(P<0.05)。结论:采用全反式维甲酸为主的治疗方案治疗低危组MDS的疗效较好,服用简单、毒副反应低,是一种有效的治疗方法。
Objective： To observe the effect of all--trans retinoic acid in the treatment of low--danger myelodysplastie syndrome （MDS）. Methods：68 cases with low--danger MDS from Mar. 2001 to Mar. 2007 were randomly divided into treatment group and control group. The control group was given folic acid, vitamin B12 and androgen, while the treatment group was added all--trans retinoic acid on the oasis of folic acid and vitamin B12. Results： The total, effective rates were 75.61% in treatment group and 48.15% in control group, the difference had statistical significance （P〈0.05）. Conclusions： All--trans retinoic acid is an effective method in the treatment of low--danger MDS which have good effect and low toxic side effect.
出处
《内蒙古中医药》
2008年第7期25-26,共2页
Inner Mongolia Journal of Traditional Chinese Medicine
