摘要
目的:探讨冠心病中医证候的分布特征,完善其常见证候的诊断标准。方法:采用整群随机抽样法对长沙地区冠心病中医证型开展临床流行病学调查,并应用聚类分析、Logistic回归分析、主成分分析等方法对资料进行分析研究。结果:①在冠心病临床流行病学调查的基础上,采用聚类分析研究症状的组合规律;②运用多元logistic回归分析和主成分分析筛选出冠心病证候的主次症状,寻找出冠心病常见证候共性的和特异性的症状指标;③初步拟定出冠心病心血瘀阻证、痰阻心脉证、寒凝心脉证、气滞心脉证、心气亏虚证、心阳亏虚证、心阴亏虚证7种基本证型的辨证标准。结论:在临床流行病学调查和现代数理统计分析基础上所建立的冠心病基本证型的辨证标准,减少了"选择性偏倚"和"测量性偏倚",较为符合临床实际。
Objective ：To explore the distribution characteristics of the TCM Syndromes of CHD ,improve the diagnostic standards of the common syndromes. Methods ：. Take the clinical epidemlological survey of the TCM Syndromes of CHD in Changsha city by whole random sampling,and then study the information by Cluster analysis Logistic regression analysis？ principal component analysis,etc. Results：①On the basis of CHD epidemlology investigation, study the law of symptom complex by cluster analysis.②elect the principal and secondary symptom of CHD Syndromes by Logistic regression analysis and principal component analysis, find out the common and specific symptom markers of CHD Syndromes. ③set up the standards of Differeciation of Syndromes of seven kinds of basic Syndromes of CHD ： Heart Blood-stasis Syndrome, Ob- struction of Heart Collaterals due to Phlegm - accumulation Syndrome , Obstruction of Heart Collaterals due to Cold - stagnation, Obstruction of Heart Collaterals due to Qi - stagnancy Syndronme, Deficiency of Heart - Qi Syndrome, Deft clency of Heart - Yang Syndrome, Deficiency of Heart - Yin Syndrome. Concluzion ： The standards of Differenciation of Syndrome based on the clinical epidemiological survey and current statistical analysis have reduced the “selection bias” and “measurement bias”, and are properly according with clinical practice.
出处
《中华中医药学刊》
CAS
2008年第8期1605-1608,共4页
Chinese Archives of Traditional Chinese Medicine
基金
国家自然科学基金资助项目(30271574)
教育部博士点基金资助(20050541005)
湖南省教育厅重点项目(04A039)
关键词
冠心病
证型
临床流行病学
标准
coronary heart disease （CHD）
syndome
clinical epidemiology
standard
