摘要细胞在接受特定的细胞外信号刺激后会产生相应的特异性生理应答。Ras／Raf／MEK／ERK信号级联通路是一条可被广泛激活的有丝分裂原活化蛋白激酶（mitogen—activated protein kinase，MAPK）通路，它能将细胞外信号传递入细胞核内，引起细胞内特异蛋白的表达谱变化，从而影响细胞命运。
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