摘要
[目的]评价高频超声对2型糖尿病（T2DM）患者颈动脉粥样硬化的诊断价值。[方法]将100例T2DM患者按病程分为三组：病程〈5年（A组）36例;5～10年（B组）31例;〉10年（C组）33例;正常对照组（D组）30例。利用高频超声探测T2DM患者的颈动脉内-中膜厚度（IMT）及粥样硬化斑块形成情况。[结果]C组的IMT、斑块发生率及斑块积分所占比率明显高于其他组（C组的IMT、斑块发生率及斑块积分分别为（0.99±0.22）mm、75.76%、（2.16±0.82）mm;A、B、D组的为（0.79±0.15）mm、（0.80±0.17）mm、（0.64±0.14）mm;36.11%、51.61%、20.0%;（1.65±0.73）mm、（1.89±0.69）、（1.23±0.62）;P〈0.05）;A组 、B组也明显高于D组（A、B组的为（0.79±0.15）mm、（0.80± 0.17）mm;36.11%、51.61%;（1.65± 0.73）mm、（1.89±0.69）;D组的为（0.64±0.14）mm、20 .0%、1.23±0.62,P〈0.05）;C组中血管受累条数及有多枚斑块的血管条数均高于其他组（C组中血管受累条数及有多枚斑块的血管条数分别为40、22;A、 B、D组的分别为17、3;26、7;9、 1;P〈0.05）;各组中软斑检出率高于硬斑及混合斑（A、B、C、D组中软斑检出率分别为：66.67%、58.82%、55.56%、70.0%;A、B、C、D组中硬斑及混合斑检出率分别为：9.52%、23.80%;11.76%、29.41%;10.0%、20.0%;P〈0.05）;各组间斑块类型所占比例差异无显著性意义,P〉0.05。[结论]T2DM患者的IMT及粥样硬化斑块形成情况,与病程密切相关。高频超声是检测T2DM患者颈动脉粥样硬化的简便而有效的方法,具有重要的诊断价值。
[Objective] To evaluate the diagnostic value of high-frequency ultrasound in detecting carotid atherosclerosis in patients of type 2 diabetes.[Methods] One hundred patients of T2DM and thirty healthy subjects were examined by high-frequency ultrasound.The intimal-medial thickness（IMT） and the atheroslerotic plaques of carotid artery were observed.[Results] There was a significant difference between C group and the other groups in IMT of carotid arteries,the plaque scores and the detection rate of plaques（P〈0.05）.So was it between A and B groups with D group.There was a significant difference between C group and the other groups in the number of abnormal vessels and vessels with multiple-plaques detection（P〈0.05）.The detection rate of soft plaque was higher than hard plague and mixed plaques（P〈0.05）.There was no difference of rate of different plaques among the four groups（P〉0.05）.[Conclusions] IMT and the carotid atheroslerotic plaques in the patients of type 2 diabetes are significantly increased with the course of diseases closely.The high-frequency ultrasound is a convenient,effective and valuable method to detect the carotid atherosclerosis of patients of type 2 diabetes.
出处
《大连医科大学学报》
CAS
2008年第4期360-362,共3页
Journal of Dalian Medical University
关键词
糖尿病
颈动脉粥样硬化
高频超声
type 2 diabetes
carotid atherosclerosis
high-frequency ultrasound
