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肺切除术后肺损伤的发生机制及肺复张策略 被引量:1

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摘要 肺切除术是普胸外科的主要手术类型,尽管手术方式及麻醉管理已有很大进步,但肺叶及全肺切除术后30d内的病死率仍高达3%~25%。肺切除术后死亡的主要原因之一是各种呼吸系统并发症,如肺不张、支气管胸膜瘘、支气管肺炎、肺水肿和急性肺损伤等。其中,肺切除术后肺损伤是一种特殊的综合征,主要表现为术后48h内开始出现呼吸困难,胸部X线摄片呈两肺弥漫性浸润影,但无左心功能衰竭或心源性肺水肿的表现,且不能与急性肺损伤(ALI)或急性呼吸窘迫综合征(ARDS)相鉴别,肺叶切除术后及全肺切除术后其发生率分别为1%~79/6及4%~7%。
作者 周波 徐美英
出处 《上海医学》 CAS CSCD 北大核心 2008年第7期518-521,共4页 Shanghai Medical Journal
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