摘要
目的通过高糖、高脂血症动物模型，观察糖、脂代谢紊乱对机体的影响及与糖尿病的关系。方法采用生化测定及放射免疫方法。结果①高糖、高脂均可使心、肾系数增加，与对照组比较差异有显著性（Ｐ＜０．０５）。②不论高糖或高脂组血糖、血脂均较对照组增高（Ｐ＜０．０１）。③高糖及高脂组ＮＯ含量、ＮＯＳ活性均较对照组降低（Ｐ＜０．０５）。结论本实验证实糖尿病时伴发的糖、脂代谢紊乱与糖尿病血管并发症的发生发展有密切关系。
Objective To make high glucose and hyperlipidemias models and study on relation between disturbance of lgucose and lipide metabolism and DM.Method With biochemistry test and radio immunity method.Result ①High glucose and hyperlipidemias could increase heart index and kidney index;②Serum glucose and lipide were increased in high glucose and hyperlipidemia group;③Both groups vasodilatory function were decreased.Conclusion There is a close relation between glucose lipide metabolism disturbance and DM complications.
出处
《潍坊医学院学报》
1997年第4期247-248,共2页
Acta Academiae Medicinae Weifang
关键词
高糖血症
高脂血症
糖尿病
病理
high glucose
hyperlipidemias
diabetes mellitus
