摘要
目的探讨血清铁蛋白(SF)水平与老年男性代谢综合征(MS)的关系。方法选择年龄>60岁男性 MS 患者60例为试验组,非 MS 者30例为对照组。所有病人均测定腹围、血压、空腹血糖、血脂、胰岛素和 SF水平,分析 SF 与老年男性 MS 的关系。结果 MS 组血清 SF 水平明显高于对照组,SF 水平与腰围(r=0.37,P=0.004)、收缩压(r=0.31,P=0.016)、舒张压(r=0.30,P=0.020)、空腹血糖(r=0.287,P=0.026)和胰岛素抵抗指数(r=0.381,P=0.004)成正相关。多因素线性回归分析,排除上述因素后,SF 与胰岛素抵抗仍独立相关(P=0.001)。结论体内铁储存过多与老年男性 MS 独立相关,其机制尚需进一步研究。
Objective To investigate the relationship between serum ferritin and metabolic syndrome in the elderly patients. Methods Waist circumference, blood pressure, fasting glucose, lipids, insulin, serum ferritin were measured in 60 male patients （age〉60 years） with MS with 30 age matched subjects without MS（NON --MS） as control. Results Serum ferritin level was significantly higher in MS patients than that in the NON-- MS controls（P〈0.01）. Serum ferritin level was significantly positive correlated with waist circumference（r= 0.37, P=0. 004） SBP（r=0.31, P=0. 016）, DBP（r=0.30, P=0.020）, fasting glucose（r=0. 287, P=0. 026） and HOMA-IR（r=0. 381, P= 0. 004）. After adjusting for waist circumference, SBP, DBP, fast glucose and HOMA-IR, SF and HOMA-IR remains independence related with MS（P=0. 001）. Conclusion Elevated iron stores is independently related to metabolic syndrome.
出处
《中华高血压杂志》
CAS
CSCD
北大核心
2008年第7期640-642,共3页
Chinese Journal of Hypertension
关键词
代谢综合征
铁蛋白
胰岛素抵抗
Metabolic syndrome
Serum ferritin
Insulin resistance
