摘要
为了解家庭因素在碘缺乏病发生中的作用，在一个重度缺碘经补碘１７年后的农村地区选取典型地方性甲状腺肿与克汀病病例１６人（病例组），同时配对选择居住同一村庄、同年龄性别的非地方性甲状腺肿与克汀病病例１６人为对照（对照组）。对３２个家庭１９３个家庭成员进行碘缺乏病现况调查。结果显示：病例组碘缺乏病病例显著高于对照组（配对秩和检验χ２＝６２３Ｐ＜００１，四格表χ２＝７９９Ｐ＜００１）。病例组家庭成员尿碘中位值显著低于对照组（χ２＝７０４Ｐ＜００１），尿碘低于０７９μｍｏｌ／Ｌ（１００μｇ／Ｌ）人数显著高于对照组（χ２＝４０９Ｐ＜００５）。作者认为为有效控制碘缺乏病，在全民食盐加碘防治碘缺乏病之后，应当充分重视该病家庭因素的作用。
To approach the role of familial factors in iodine dificiency disorder(IDD),193 family members in the 16 families with IDD(case)and 16 families without IDD(contral)respectively were tested in a severe iodine deficiency area in Shanxi,ChinaThe results showed that the prevalence of IDD was higher in the case than that in the control(rank sum χ2=623 P<001 and fourfold table χ2=799 P<001) The median of urnary iodine and the number of the persons with lower than 079 μmol/L significantly were higher in the case than that in the contral(χ2=704 P<001,andχ2=409 P<005 respectively),suggesting it should pay more attention to the role of familial factors in the control IDD
关键词
甲状腺肿
克汀病
碘缺乏病
家庭聚集性
goiter,endemic
critinism
iodine deficiency disorder
family assemblage
