摘要
作者报告了江苏省在风疹疫苗使用前人群的自然免疫状况，４岁以下年龄组血凝抑制（ＨＩ）抗体阳性率在２５％以下，随着年龄的增长，自然免疫水平增高，１３～２５岁人群阳性率约在８０％左右。接种风疹疫苗１月后，抗体１００％阳转，ＧＭＴ从免前的１３．３３上升至２４３．１６，说明国产ＢＲＤⅡ株风疹减毒活疫苗具有良好的免疫原性。对于免前阳性人群。
The natural immunity status in different age groups was investigated. The positive rate of HI antibody under the age of 4 was less than 25%. The natural immunity level increased gradually with age and the positive rate of the antibody reached 80% among the group aged 13-25.Rate of seroconversion was 100% in any age group one month after immunization,and GMT rose from 13.33 to 243.16. It was suggested that immunogenicity of domestic attenuated live rubella vaccine BRD Ⅱ was satisfactory. For the population with positive antibody before immunization,the total GMT rose from 189.59 to 259.00 after vaccination and the difference between immunization before and after was highly significant. According to the above result,we suggested that the vaccination strategy for rubella among young children and women of child bearing age should be implemented.
出处
《中华流行病学杂志》
CAS
CSCD
北大核心
1997年第4期227-229,共3页
Chinese Journal of Epidemiology
关键词
风疹
疫苗
免疫应答
Rubella vaccine Immune response
