摘要
目的：探讨外周血染色体异常与流产、死胎、畸胎的关系。方法：对2001年5月~2007年4月到吉林大学特殊疾病检测站进行遗传咨询的272例患者进行外周血淋巴细胞培养,进行染色体核型分析。结果：272例生育异常患者共检出与流产、死胎、畸胎相关的异常核型22例,包括女性染色体异常5例,男性染色体异常17例。结论：染色体核型异常是导致流产、死胎、畸胎的重要原因之一,且男性多于女性,夫妇双方都应当进行细胞遗传学染色体检查,有助于生育指导。
To study the relationships between abnormal karyotypes of the patient＇s peripheral blood and the abortion, stillbirth fetus and teratism. Methods： By investigate 272 outpatients with genetic counseling in detection station of special disease, Jilin University from May 1, 2004 to April 30, 2007. Their peripheral lymphocytes were cultured and the abnormal karyotypes were analyzed. Results： There were 22 cases of abnormal karyotypes in 272 patients with genetic counseling. Of which, 5 cases were female abnormal karyotypes; 17 cases were male. Conclusion： The abnormal karyotype is one of important reasons which causes of the abortion, stillbirth fetus and teratism. Male is more than female. They can gain procreative instruction by investigate couple＇chromosome of cytogenetics＇methods.
出处
《中国妇幼保健》
CAS
北大核心
2008年第10期1391-1393,共3页
Maternal and Child Health Care of China
基金
吉林省计划委员会项目〔2004〕987
关键词
染色体异常
核型
流产
死胎
畸胎
Chromosomal abnormality
Karyotype analysis
Abortion
Stillbirth fetus
Teratism
