摘要
对３０例ＡＦＰ阴性原发性肝癌（ＰＨＣ）伴腹水患者用放射免疫分析（ＲＩＡ）进行血清及腹水ＣＥＡ、ＣＡ５０含量联合检测，并与２６例ＡＦＰ阳性ＰＨＣ伴腹水患者、３５例肝硬化腹水患者的血清及腹水ＣＥＡ、ＣＡ５０含量作比较。结果显示：ＡＦＰ阴性ＰＨＣ组血清及腹水ＣＥＡ含量平均值均显著增高，阳性率７３．３％，而ＡＦＰ阳性组的阳性率为３０．８％，两组ＣＥＡ含量比较Ｐ＜０．０１，两组ＣＡ５０含量比较无显著性差异（Ｐ＞０．０５）；但两组与肝硬化腹水组对比则呈非常显著与显著性差异（对于ＣＥＡ，Ｐ＜０．００１－０．０１；对于ＣＡ５０，Ｐ＜０．０５））。结果提示：对ＰＨＣ患者特别是ＡＦＰ阴性者进行ＡＦＰ、ＣＥＡ、ＣＡ５０联合检测有临床实用价值。
Taking advantage of RIA method, the combined detection of CEA and CA50 in serum and ascites for 30 cases with AFP negative of PHC are carried out. Comparing with the AFP positive group and hepatocirroneum ascites group, The contents of AFP、CEA and CA50 are markedly high for the AFP negative group.Data indicate that the combined detection of AFP、CEA and CA50 is valuable in clinic practice for patients with PHC, especially for ones with AFP negative.
出处
《同位素》
CAS
1997年第2期124-126,共3页
Journal of Isotopes
关键词
原发性
肝癌
甲胎蛋白
放射免疫分析
糖类抗原
primary hepatic carcinoma(PHC) ascites α fetoprotein carcinoma embryo antigen(CEA) carbohydrate antigen50(CA50)
