摘要
目的：观察硬膜外分娩镇痛时对胎儿血气分析结果及产程、母婴的影响。方法：240例产妇随机分为镇痛组和对照组：镇痛组120例，采用0．125％布比卡因，负荷量8～10mL，持续量4mL／h，产妇自控硬膜外镇痛（PCEA）；对照组120例，自然分娩者。比较两组产妇脐动、静脉血气分析、SBP、DBP、HR、SPO2、总产程（第1、第2产程时间）、新生儿Apgar评分、视觉模拟评分（VAS）。结果：①两组新生儿脐血血气分析指标测定值均在正常范围，总产程比较，差异无统计学意义；②两组新生儿出生后5minApgar评分均为8分以上；（张痛药起效后产妇疼痛明显减轻，宫缩时仅感腹部发紧、发胀，双下肢无麻木感，活动自如。两组产妇VAS在镇痛前、后差异有统计学意义（P〈0．05）。结论：0．125％布比卡因用于镇痛效果可靠，不延长产程，对新生儿无不良影响。
Objective： To observe the influences of epidural delivery analgesia during labor on fetal blood gas analysis and the birth process. Methods： 240 cases of lying - in women were divided randomly into maternal analgesia group （n = 120）and the control group（ n =120）. The analgesia group used 0. 125% bupivacaine, load 8 -10 ml, sustained in 4 ml/h, maternal -controlled epidural analgesia （PCEA） . The control group was natural childbirth. The umbilical artery and venous blood gas analyses, SBP, DBP, HR, SPO2, the birth process, neonatal Apgar score and visual analog score （VAS） were determined and compared between two groups. Results. （1）The indices of neonatal cord blood gas analysis were in the normal range for both groups. The comparison of middle birth process showed not significant difference. （2）Apgar scores were more than eight points at 5 min after birth for both groups. （3） The analgesics significantly reduced pain when it worked, the only sense was the abdominal tight expansion and no lower limbs numbness when uterine contraction. VAS index showed a significant difference （P 〈 0.05 ） before and after analgesia. Conclusion： 0. 125% bupivacaine has reliable analgesic effect and no lasting birth process and no adverse effects on newborns.
出处
《海南医学院学报》
CAS
2008年第4期390-391,394,共3页
Journal of Hainan Medical University
基金
深圳市龙岗区科技局科研立项项目(20030115)
关键词
布比卡因
分娩
镇痛
产科
血气分析
Bupivacaine
Labour
Analgesia, obstetrics
Blood gas analysis
