摘要
用黄芪生药1250～5000mg／kg，连续给药小鼠5d，其A6组分对100LD50或100ID50感染的BALB／C小鼠都有明显的预防和治疗作用，可降低感染幼鼠的死亡率和延长其平均存活天数；降低感染成年鼠的肺湿重。经X2和t检验，有显著性差异。且预防效果优于治疗。早期给药疗效较好。
The preventive and curative effects of Astragalus membranaceus Bungo A6 on the mice in-fected with influenza virus FM1 strain were studied. The results showed that the gruffs concentra-tion of Astragalus membranaceus Bungo was the range of 1250~ 5000 mg/kg. d×5. The preven-tive and curative effects of the A6 constituent on the BALB/C mice infected with 100 LD50 or 100 ID50 FM1 were very obvious. The mortality and the mean survial days of the infected infantile mice were reduced and prolonged. The lung humid weight of the infected mature mice were lightened (P < 0.001 ~ 0.05). In addition, the preventive effects were better than the curative effects.The earlier the drug was given, the better the curative effects were showed.
出处
《中国病毒学》
CSCD
1997年第4期342-345,共4页
Virologica Sinica
基金
贵州省科委基金
关键词
黄芪
流行性感冒病毒
感染
防治
中药
Astragalus membranaceus, Influenza virus, Mice, Drug effective section
