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青海枸杞叶提取物对低氧递增游泳训练小鼠运动能力的影响

Effect of extract in Qinghai lycium barbayium leaf on the exercise capacity of hypoxic acute exercise mice
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摘要 目的:观察青海枸杞叶提取物对低氧递增游泳训练小鼠运动能力的影响。方法:①60只雄性健康小鼠,随机分为安静对照组、递增游泳训练组、递增游泳训练+青海枸杞叶提取物组,每组20只。②递增游泳训练组,递增游泳训练+青海枸杞叶提取物组进行4周的低氧递增游泳训练。③递增游泳训练+青海枸杞叶提取物组在训练期间每天以青海枸杞叶提取物水溶液灌胃。④4周后记录小鼠力竭游泳时间和血乳酸、丙二醛含量、血乳酸脱氢酶、超氧化物歧化酶、谷胱甘肽过氧化物酶活性。结果:①小鼠力竭游泳时间:递增游泳训练组小鼠力竭游泳时间显著短于递增游泳训练+青海枸杞叶提取物组(P<0.05)。②血乳酸含量、乳酸脱氢酶活性、丙二醛含量:递增游泳训练组显著高于递增游泳训练+青海枸杞叶提取物组(P<0.05)。③血超氧化物歧化酶、谷胱甘肽过氧化物酶活性:递增游泳训练组显著低于递增游泳训练+青海枸杞叶提取物组(P<0.05)。 Objective :Effect of extract in Qinghai lycium barb-ayi-um leaf on the exercise capacity of hypoxic acute exercise mice.Methods : ①60 mice were divided into three groups, namely control group, training group, training +QLBL group, with 20 mice in each; ②The swimming training was performed in the mice of training group and training +QLBL group,for four weeks; ③Everyday the mice of training +QLBL groupwere iniected intragastrically with qinghai lycium barbariuum Leaf.④After four weeks, the mice's exhaustive swimming time, blood LDH activity, SOD activity, C;SH-PX activity and MDA, BLA content were determined after exhaustive swimming.Conclusion : ①The exhaustive swimming time of mice: The time of training +QLBL group was significantly longer than that of training group (P〈0.05).②The LDH activity and MDA, BLA content: They were all increased significantly in training group, compared with training +QLBL group ( P〈0.05 )③Blood SOD activity and GSH-PX activity of training group was significantly lower than those of training +QLBL group ( P〈0.05 ).
机构地区 青海大学医学院
出处 《辽宁中医药大学学报》 CAS 2008年第7期141-143,共3页 Journal of Liaoning University of Traditional Chinese Medicine
关键词 枸杞叶 运动能力 BLA MDA lycium barbariuum leaf exercise capacity BLA MDA
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