摘要
目的评价0.25%托吡卡胺滴眼液治疗青少年假性近视的临床效果,探讨0.25%托吡卡胺滴眼液治疗青少年假性近视的临床应用价值。方法回顾性抽取2004年6月至2007年6月间,在我院眼科门诊首次诊断为假性近视的患者,应用0.25%托吡卡胺眼液每晚滴眼并追踪观察、资料完整的青少年100例（200眼）,用0.5%复方托吡卡胺眼液滴双眼,每5分钟一次,共6～8次,滴最后一次的30 min后检影验光并试镜矫正视力。记录散瞳前后裸眼视力、散瞳后的静态屈光度和矫正视力,然后给予0.25%托吡卡胺眼液滴眼,每晚睡前2次,间隔10 min一次,连续滴眼14 d为一疗程。14 d后再用上述验光方法作第2次检影验光,记录散瞳前后裸眼视力,散瞳后的静态屈光度和矫正视力。结果治疗后散瞳验光前裸眼远视力均呈提高,差异有统计学意义（P〈0.01）;治疗后静态屈光状态呈大部分近视度数降低,差异有统计学意义（P〈0.01）。结论0.25%托吡卡胺滴眼液防治青少年假性近视疗效确切,可推荐作为防治青少年假性近视的首选药物。
Objective To evaluate the clinical effects and value of 0.25 % tropicamide topically dropped in treatment of adolescent pseudo myopia.Methods This was a retrospective,consecutive study,which included 100 adolescents who were firstly diagnosed psudo myopia and then prescribed with 0.25 % tropincamide topically dropping every night at our hospital between June,2004 and June,2007 with intact records.The uncorrected distance acuity before mydriasis was recorded.The uncorrected distance acuity,BCVA and static diopters after mydriasis were recorded 30 minutes after 6 to 8 drops of 0.5 % compound tropicamide every 5 minutes.The patients were then topically dropped with 0.25 % tropicamide twice a day at night,at intervals of 10 minutes.The above parameters were recorded after 14 days＇ medication.Results The uncorrected distance acuity before the mydriasis were all improved（P〈0.01） and the static diopters decreased（P〈0.01） in most patients after treatment.Conclusion 0.25% tropicamide is effective in treatment of adolescent pseudo myopia and can be recommended as primary treatment.
出处
《临床医学》
CAS
2008年第6期31-32,共2页
Clinical Medicine
