摘要
目的研究丙泊酚、丙泊酚和芬太尼在老年人无痛胃镜过程中血糖及循环的影响。方法80例无痛胃镜检查老年患者（年龄65．91岁），随机分为A组（n=40），经静脉推注异丙酚（1．5～2．5mg／kg）与Bgt（n=40），先经静脉滴人芬太尼25．50μg，后静脉推注丙泊酚（1．0—2．5mg／kg）。当患者对言语指令无反应和睫毛反射消失时置人胃镜，监测进镜前、进镜后5min、10min SBP、DBP、MAP、RR、HR，SPO：值。结果A组血糖进镜后5min和10min虽有增加，但与进镜前比较差异无统计学意义（P〉0．05）。B组进镜后血糖均有明显升高，且与进镜前比较差异有显著性（P〈0．05或P〈0．01）。结论丙泊酚、丙泊酚和芬太尼均能不同程度抑制胃镜检查进镜时的应激反应，但在本组病例中，丙泊酚优于丙泊酚和芬太尼。
Objective To study the effects on blood sugar and circulate of propofol or propofol and fentanyl used for painless gastroscopy in elderly patients. Methods Eighty elderly patients for gastroscopy（aged between 65 -91 ） were randomly divided into group A（ n = 40） , who was intravenously injected propofol （1.5 -2.5mg/kg） into and group B（ n = 40） ,in which patients were given 25 ～ 50μg of fentanyl intravenously before propofol （1.0 ～ 2.5mg/kg） was injected intravenously. The gastroscope was inserted when patient felt unconsciousness and unreactive to dictation. Meantime,SBP, DBP, MAP, RR, HR, SPO2 were monitored at 5,10 minutes before insertion and 5,10minute after insertion. Results The blood sugar of group A went up at 5,10minute after insertion. , But there was no significant difference between before gastroscope insertion and after gastroscope insertion （ P 〉 0.05 ）. The blood sugar of group B was significantly higher after gastroscope insertion,There was significant difference between pre - insertion and post - insertion （ P 〈 0.05 or P 〈 0.01 ）. Conclusion propofol or propofol and fentanyl can restrain the stress respose to gastroscope insertion to various degrees, but restrain effects of propofol are better than that of propofol and fentanyl in this case.
出处
《医学研究杂志》
2008年第6期96-98,共3页
Journal of Medical Research
关键词
无痛胃镜
丙泊酚
应激反应
老年人
Painless gastroscope
Propofol
Stress respose
Elderly patients
