摘要
目的探讨内镜光动力微创疗法（PDT）在胆管癌治疗中的作用。方法对本院于2005年10月至2007年4月在常规综合治疗的基础上，开展内镜下的光动力微创治疗的15例胆管癌患者的相关临床资料进行回顾性总结分析。结果15例患者在PDT治疗后均取得良好效果，治愈3例，好转12例，除1例出现光敏性皮炎、3例出现术后胆道感染外，均未出现严重并发症。至目前为止，仍存活10例，中位生存期达243d（163～575d）。在随访期患者保持稳定的生活质量。结论内镜光动力联合微创治疗在胆管癌综合治疗中，具有创伤少、疗效好、并发症少的特点，对于提高胆管癌综合治疗的效果，提高生活质量及延长患者的生存期有重要的临床意义。
Objective To investigate the role of endoscopic application of photodynamic therapy （PDT） for cholangicarcinoma. Methods Clinical data of 15 cholangicarcinoma patients who were treated with endoscopic application of photodynamic therapy between Oct 2005 and Apr 2007 were analyzed retrospectivly. Re.suits No relevant adverse events from PDT occurred except for minor intraoperative phototoxicity in one patient and infectious complication in 3 patients. Ten patients were still alive. The median survival time was 243 days （ 163 - 575 d）. Quality of life in all patients remained stable throughout follow-up period. Conclusions Endoscopic application of photodynamic therapy has a clinical value for prolonging survival time of patients with cholangicarcinoma. This treatment is minimally invasive and has a low complication rate.
出处
《中华生物医学工程杂志》
CAS
2007年第5期283-285,共3页
Chinese Journal of Biomedical Engineering
基金
广东省科技计划项目（2005830501009）
关键词
胆管肿瘤
光动力疗法
内窥镜疗法
Bile duct neoplasm
Photodynamic therapy
Endoscopic therapy
