摘要
目的探讨内镜下逆行性胆管活检的可行性、安全性及敏感性,获取胆管粘膜组织病理学,指导临床治疗。方法在传统的影像学方法如CT、MRCP等基础上,对非结石引起的梗阻性黄疸患者共16例进行常规ERCP,并直接将活检钳送入胆管病变处活检,送病理科检查。结果16例患者中有14例获得病理组织,成功率为87.5%,无并发症发生。病理诊断为胆管癌5例、胰腺癌2例、转移癌2例、肝细胞癌1例、炎性表现4例,阴性结果4例,阳性结果10例。结论内镜下逆行性胆管活检术虽受设备及内镜医生技术影响,但它的确是一种准确可靠获取组织病理学检查的途径,对指导胆管梗阻性黄疸患者治疗非常有帮助。
[Objective] To explore the technical feasibility, safety and sensitivity of endoscopic retrograde biliary biopsy in obstructive jaundice, and guide clinical treatment of the disease. [Methods] On the basis of traditional medical imaging such as CT and MRCP, endoscopic retrograde bihary biopsy was done in 16 patients with noncaculous obstructive jaundice through ERCP, and then the tissues were sent for histopathological examination was done. [Results] The histopathologic diagnosis was acquired in 14 of 16 patients, the sensitivity was 87.5%, No complications were noted. Pathological reports included cholangiocarcinoma （n = 5）, pancreatic adenocarcinoma （n = 2）, metastastic carcinomas （n = 2）, hepatic carcinoma （n = 2）, inflammation （n = 4）. The carcinoma diagnosis was acquired in 10 of 14 patients. [Conclusions] The success rate of endoscopic retrograde biliary biopsy is affected by skills of endoscopists and equipments, but it is one of the accurate and reliable ways to acquire histopathological diagnosis. The technology of endoscopic retrograde biliary biopsy is significantly useful in the management of patients with biliary obstructive jaundice.
出处
《中国内镜杂志》
CSCD
北大核心
2008年第5期491-492,496,共3页
China Journal of Endoscopy
基金
深圳市科技计划项目(No.:200702026)
