摘要
目的观察慢性肺心病呼吸衰竭患者参芎注射液治疗前后血浆D-二聚体、纤维蛋白原(Fg)、动脉血氧分压(PaO_2)水平的变化情况。方法256例患者随机分为两组:对照组采用常规治疗,治疗组在常规治疗的基础上加用参芎注射液200 ml静脉滴注,治疗14 d后观察D-二聚体、Fg、PaO_2水平变化。采用ELISA方法测定血浆D-二聚体,采用半自动血凝仪检测Fg,动脉血气分析测定PaO_2。结果慢性肺心病呼吸衰竭患者治疗后血浆D-二聚体、Fg、PaO_2水平较治疗前均明显改善,且治疗组血浆D-二聚体、Fg较对照组下降明显,差异有统计学意义(P<0.05)。结论参芎注射液可改善慢性肺心病呼吸衰竭患者体内高凝状态、改善缺氧。
Objective To study the changes of D - dimer,fibrinogen and PaO2 in the patients with chronic cor pulmonale with respiratory failure. Methods On the 14th after treatment, D - dimer, Fg and PaO2 levels of 148 patients as treatment group were determined and compared with those of 108 patients as control group. It was additional Shenxiong injection treatment in patients of treatment group. Results The levels of D- dimer,fibrinogen and PaO2 in the two groups after treatment were improved significantly compared with that at the begining of treatment （ P 〈 0. 05 ）, compared with the control group, plasma D - dimer, fibrinogen levels in treatment group decreased significantly. Conclusion Shenxiong injection could improve hypercoagulable state and hypoxia in the patients of chronic cor pulmonale with respiratory failure.
出处
《中国实用医药》
2008年第17期10-11,共2页
China Practical Medicine
