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3种拉唑类三联疗法治疗幽门螺杆菌感染的成本-效果分析 被引量:12

Cost-Effectiveness Analysis of Triple Therapeutic Schemes of Prazoles for Hp Infection
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摘要 目的:探讨不同给药方案治疗幽门螺杆菌(Hp)感染的经济学效果。方法:102例Hp感染的消化性溃疡患者随机分为3组,给予奥美拉唑+阿莫西林+胶体果胶铋(A组)、雷贝拉唑+阿莫西林+胶体果胶铋(B组)、泮托拉唑+阿莫西林+胶体果胶铋(C组),采用成本-效果分析法进行评价。结果:A、B、C组的Hp清除率及溃疡愈合率的成本-效果比分别为1027.31、976.79、967.40及921.05、915.77、936.16。结论:B组方案较佳。 OBJECTIVE: To evaluate the economic .effectiveness of different pharmacotherapentic schemes of Prazoles for helicobacteria pylori (Hp) infection. METHODS: 102 patietns with peptic ulcer were randomly assigned to receive Omeprazole + amoxicillin + Colloidal bismmth pectin (Group A), Rabeprazole + Amoxicillin + Colloidal bismmth pectin (Group B) or Rebeprazole + amoxicillin + Colloidal bismmth pectin (Group C) . The cost- effectiveness analysis was conducted on the three schemes. RESULTS: The cost - effectiveness ratios of groups A, B and C on Hp clearance rates were 1 027.31, 976.79 and 967.40, respectively, and on peptic ulcer healing rates were 921.05, 915.77 and 936.16, respectively. CONCLUSION: Scheme B is the best one for Hp infection.
出处 《中国药房》 CAS CSCD 北大核心 2008年第17期1289-1291,共3页 China Pharmacy
关键词 奥美拉唑 雷贝拉唑 泮托拉唑 幽门螺杆菌感染 成本-效果分析 Omeprazole Rabeprazole Pantoprazole Hp infection Cost - effectiveness analysis
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