摘要
对胰及胰周坏死组织感染病例的临床危险因素作一回顾性病例对照分析。以76例急性重症胰腺炎患者为研究对象，其中32例经手术证实并发胰及胰周坏死组织感染为感染组，另44例未并发胰及胰周坏死组织感染为对照组。结果显示：感染与年龄、病因、早期休克、呼吸衰竭及胃肠外高营养无关（OR0．78～1．26，P＞0．05），而与早期诊断性或治疗性胰及胰周穿刺、引流、早期手术及重度肠麻痹有关（OR3．02～5．48，P＜0．05）。因此，在急性胰腺炎早期的临床治疗中应从严掌握穿刺和手术指征，并限制阿托品等加重肠麻痹的药物使用。
<Abstrast>A review of Patients with acute pancreatitis treated in this hospital in recent 1O years was made.Todetrmine the risk factors of septic necrosis in and around the pancreas,32 cases with septic necrosis which wereproved in surgical operation and 44 cases without septic necrosis(as control)were inchided in this Study. The possiblefactors were comparaively analysed. The results showed that septic necrosis in and around the pancreas obviously relat-ed to the diagnostic or therapeutic puntures, early surgical drainage and paralytic ileus(OR 3.02-5.48, P < 0.05),but there were no associations with age, etiology, shock, respiratory failure and total penteral nutrition(OR 0.78 -1 .26, P > 0.05) .The authers suggest that either pancreatic, peripancreatic puncture or early surgical drainage shouldbe limited and any medication which makes paralytic ileus deteriorated such as atropine should be avoided in the treat-ment of acute Pancreatitis.
关键词
急性
胰腺炎
感染
胰周坏死组织
Acute pancreatitis ,Necrosis infection, Risk factor
