期刊文献+

炎性因子与妊娠期糖尿病的相关研究 被引量:1

Correlated Study of Inflammation Cytokines and Gestational Diabetes Mellitus
下载PDF
导出
摘要 妊娠期糖尿病是指妊娠后才发生或首次发现的糖尿病,是妊娠的高危因素之一。目前妊娠期糖尿病的病因与发病机制尚未完全阐明,近年来炎症学说备受关注。炎性因子包括C反应蛋白、肿瘤坏死因子α、白细胞介素系列(IL-6、IL-10等)、血清铁蛋白等。有关研究发现,炎性因子介导的慢性炎性反应参与妊娠期糖尿病的发病。 Gestational diabetes mellitus is the diabetes firstly found or occurred after pregnancy,which is the one of high risks in pregnancy.However,its etiology and pathogenesis is not very clear at present.The inflammatory theory is attracting more attention in recent years.Inflammatory cytokines includes c-reactive protein,tumor necrosis factor-αand interleukin-6,interleukin-10,ferritin and so on.Related studies showed that chronic inflammation induced by inflammatory cytokines took part in the genesis of gestational diabetes.
作者 杨芳 黄星
出处 《医学综述》 2008年第11期1700-1702,共3页 Medical Recapitulate
关键词 妊娠期糖尿病 病因学 炎性因子 Gestational diabetes mellitus Etiology Inflammatory cytokines
  • 相关文献

参考文献26

  • 1Wolf M, Sauk J, Shah A, et al. Inflammation and glucose intolerance : a prospective study of gestational diabetes mellitus [ J ]. Diabetes Care,2004,27( 1 ) :21-27. 被引量:1
  • 2曾丽,朱宁湖,周才.血清C-反应蛋白水平对妊娠糖尿病诊断的价值[J].海南医学,2006,17(7):75-76. 被引量:7
  • 3Qiu C,Sorensen TK, Luthy DA, et al. A prospective study of maternal serum C-reactive protein(CRP) concentrations and risk of gestational diabetes mellitus [ J ]. Paediatr Perinat Epidemiol,2004,18 (5) :377-384. 被引量:1
  • 4Retnakaran R, Hanley A J, Raif N,et al. C-reactive protein and gestational diabetes:the central role of maternal obesity[ J]. J Clin Endocrinol Metab,2003,88 ( 8 ) :3507-3512. 被引量:1
  • 5Ramsay JE, Ferrell WR, Crawford L, et al. Maternal obesity is associated with dysregulation of metabolic, vascular, and inflammatory pathways [ J ]. J Clin Endocrinol Metab ,2002,87 (9) :4231-4237. 被引量:1
  • 6Visser M, Bouter LM, Ceraldine M. Elevated C-reactive protein levels in overweight and obese adults [ J ]. JAMA, 1999,282 ( 22 ) : 2131-2135. 被引量:1
  • 7Kirwan JP,Mouzon SH,Lepercq J,et al. TNF-α is a predictor of insulin resistance in human pregnancy [ J ]. Diabetes, 2002,51 (7) :2207-2213. 被引量:1
  • 8Chen HL, Yang YP, Hu XL, et al. Tumor necrosis factor alpha mRNA and protein are present in human placental and uterine cells at early and late stages of gestation [ J ]. Am J Pathol, 1991,139 (2) :327-335. 被引量:1
  • 9Coughlan MT, Oliva K, Georgiou HM, et al. Glucose-induced release of tumour necrosis factor-alpha from human placental and adipose tissues in gestational diabetes menitus [ J ]. Diabet Med, 2001,18( 11 ) :921-927. 被引量:1
  • 10Rui L,Aguirre V,Kim JK,et al. Insulin/IGF-1 and TNF- stimulate phosphorylation of IRS-1 at inhibitory Ser307 via distinct pathways [J]. J Clin Invest,2001,107(2) :181-189. 被引量:1

二级参考文献16

  • 1曹泽毅.中华妇产科学[M].北京:人民卫生出版社,1999.2129. 被引量:3234
  • 2Wolf M,Sandler,Hsu K,et al.First-trimester C-reactive protein and subsequent gestationak diabetes[J].DiabetesCare,2003,26(3):819-824. 被引量:1
  • 3Ford ES.Boby mass index,diabetes,and C-reactive protein among U.S.adults[J].Diabetes Care,1999,22(12):1971-1977, 被引量:1
  • 4BarzilayJ I,Abraham L,Heckberts R,et al.Therelation of markers of inflammation to the development of glucose disorders in the elderly:the cardiovascular health study[J],Diabetes,200150(10):2384-2389. 被引量:1
  • 5Qiu C,Sorensen TK,Luthy DA,et al.A prospective study of matermal serum C-reactive protein (CRP)concentrations and risk of gestational diabetes mellitus[J],Paediat Perinat Epidemiol,2004,18 (5):377-384. 被引量:1
  • 6Buchanan TA.Pancreatic B-cell defects in gestational diabetes:implications for the pathogenesis and prevention of type 2 diabetes[J].J Clin Endocrinol Metab,2001,86(3):989-93. 被引量:1
  • 7Pradhan AD,Manson JE,Rifai N,et al.C-reactive protein,interleukin6,and risk of developing type 2 diabetes mellitus[J].JAMA,2001,286(3):327-34. 被引量:1
  • 8Expert Committee on the Diagnosis and Ckassification of Diabetes Mellitus.Report of the expert committee on the diagnosis and classification of diabetes mellitus[J].Diabetes Care,2003,26(Suppl1):S5-20. 被引量:1
  • 9Guerrero-Romero F,Rodriquez-Moran M,Gonzalez-Ortiz M,et al.Early decrease of the percent of HOMA beta-cell function is independently related to family history of diabetes in healthy young nonobese individuals[J].Diabetes Metab,2005,3(4 pt 1):382-6. 被引量:1
  • 10Kekki M,Kurki T,Kotomaki T,et al.Cost-effectiveness of screeing and treatment for bacterial vaginosis in early pregnancy among women at low risk for preterm birth[J].Acta Obstet Gynecol Scand,2004,86(1):2-3. 被引量:1

共引文献38

同被引文献5

引证文献1

二级引证文献5

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部