摘要
通过对硝基甲烷先进行溴代反应生成溴代硝基甲烷,再与甲醛进行加成反应的新方法合成布罗波尔,不仅避免了使用有毒易燃非极性有机溶剂,而且使产品的总收率达到912%。
A new approach is introduced about bromination of the nitroalkane prior to the aldol reaction to synthesize bronopol which is no usage of organic solvents those are either flammable,toxic,or both,but raising the overall yield to 91.2%.The method is beneficial for industrial production.
出处
《精细化工》
EI
CAS
CSCD
北大核心
1997年第5期47-49,共3页
Fine Chemicals