摘要
了解本地区在采用常规抗生素治疗支原体后多重耐药株的产生情况，为临床针对性用药提供科学依据。采用培养法对女性生殖道炎患者分泌物进行支原体培养、体外药敏试验及分析。结果可见，感染数量≥10^4cfu／mL的支原体阳性率为52．9％（82／155）；13种抗生素中，耐药种数构成比为6R〉2R、4R、5R〉3R〉lR〉8R〉7R、10R〉OR〉9R、12R、13R；耐药率为林可霉素〉壮观霉素〉环丙沙星〉诺氟沙星〉司帕沙星〉罗红霉素〉氧氟沙星〉克拉霉素〉左氧氟沙星〉阿齐霉素〉强力霉素，美满霉素〉交沙霉素。体外药敏试验对临床治疗支原体感染及减少多重耐药株的产生具有重要指导意义。
The emergence of multi-resistant Mycoplasma strains after adopting routine antibiotic treatment in the region was investigated in order to provide scientific proofs in the clinic medical cure with a clear aim. Cultivation method was adopted to culture Mycoplasma from feminine patients suffer from genital tract inflammation, and tested and analyzed in vitro on medical sensitivity. The results showed that among 155 cases, the positive rate of Mycoplasma of more than 10^4 cfu/mL was 52.9% （82/155） ; and among 13 antibiotics the numbers of drug resistance that made up the proportion was 6R 〉2R, 4R, 5R 〉3R 〉 1R 〉SR 〉7R, 10R 〉OR 〉9R, 12R, 13R; and the resistance rate were Lincomycin 〉 Spectinomycin 〉 Ciprofloxacin 〉 Norfloxacin 〉 Sparfloxacin 〉 Roxithromycin 〉 Ofloxacin 〉 Clarithromycin 〉 Levofloxacin 〉 Azithromycin 〉 Doxycycline, Minocycline 〉 Josamycin. Therefore, sensitivity tests in vitro of medicine have important instructive significance for clinical treatment against Mycoplasma infection and reducing the emergence of the multi-resistant strains.
出处
《微生物学杂志》
CAS
CSCD
2008年第2期71-73,共3页
Journal of Microbiology
关键词
解脲脲原体
人型支原体
支原体感染
药敏
多重耐药性
Uriaplasma urealyticum
Mycoplasma homins
Mycoplasma infection
medicine sensitivity test
multi-resistance
