摘要
目的:探讨维思通治疗精神分裂症阴性症状的疗效及不良反应。方法:采用随机对照研究方法,用维思通和舒必利分别治疗以阴性症状为主的精神分裂症。疗程12周,以BPRS、SANS评定疗效,以TESS评定药物不良反应。结果:两药对精神分裂症阴性症状疗效近似,维思通对意志缺乏、兴趣缺乏及社交缺乏改善明显,不良反应少且轻微。结论:维思通对精神分裂症阴性症状有一定疗效。
Objective：To compare the clinical efficacy and side effects of risperidone and sulpiride in the treatment of schizophrenia with predominantly negative symptoms. Methods：two hundred shizophrenic inpatients with predominantly negative symptoms were randomly assigned to risperidone group or sulpiride group for 12 weeks. The clinical efficacy and side effects were evaluated with BPRSSANS, SANS, and TESS respectively. Results： the clinical efficacy of risperidone and sulpiride are similar ,but risperidone was more efficacy for treatment of abulia, interest deficiency and social withdrawal The side effects of risperidone are few. Conclusions： risperidone is highly effective to treat negative symptoms of schizophrenia.
出处
《中国民康医学》
2008年第11期1160-1160,1162,共2页
Medical Journal of Chinese People’s Health
关键词
维思通
舒必利
精神分裂症
阴性症状
Risperidone
Sulpiride
Schizophrenia
Negativesymptoms
