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胰高血糖素样-1及其类似物与糖尿病治疗

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摘要 胰高血糖素样肽-1(glucagons-1ike peptide-1,GLP-1)是一种典型的脑-肠轴激素,在中枢由孤束核、背侧及腹侧髓质、嗅球的神经元核周体产生;在外周由分布于空肠、回肠和盲肠的神经内分泌L-细胞分泌,在体内以多种形式存在。人体进餐或口服葡萄糖后,L-细胞被激活,导致GLP-1被迅速释放入血液中,加强胰岛素的合成与分泌。
出处 《中华全科医师杂志》 2008年第6期391-392,共2页 Chinese Journal of General Practitioners
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