摘要
目的观察伤科散外敷对急性闭合性软组织损伤的疗效和安全性。方法100例患者随机分成治疗组和对照组各50例,分别在患处外敷伤科散和701跌打镇痛膏,每天1次,治疗1个疗程共7d。观察各组疼痛、压痛、肿胀、瘀斑、功能障碍的改善情况。同时治疗组检查治疗前后血常规、尿常规、大便常规、肝功能、肾功能。结果治疗组疼痛、压痛、肿胀、瘀斑、功能障碍等症状计分显著低于对照组(P<0.05)。治疗组痊愈17例,显效20例,有效13例,无效0例,总有效率为100.0%,优于对照组(P<0.05)。对急性软组织挫伤、急性关节扭伤不同类型损伤的疗效也显著性优于对照组(P<0.05)。治疗组治疗前后实验室检查未见异常。结论伤科散外敷具有良好的活血化瘀、消肿镇痛作用,其临床疗效好于701跌打镇痛膏,且无肝肾损害等不良反应,安全性好。
Objective To observe the therapeutic effect and safety of shangkesan for acute closed injury of parenchyma. Methods 100 cases were randomly divided into two groups. Fifty patients in group one were externally applied with shangkesan and another group （ 50 patients ） with 701 paste. After 7-day treatment, the reduction of pain, tendness, swelling, ecchymosis and dysfunction was assessed. Meanwhile, three routine examinations, liver and kidney function tests were conducted to each group. Results Compared to that in the controls, the symptom scores of pain, tendness, swelling, ecchymosis and dysfunction in shangkesan group were reduced markedly（P 〈0.05 ） and the treatment effect was improved（ P 〈 0.05） with a total effective rate of 100.0% （ 17 cases were healed, none was ineffective） . Abnormal reports of three routine examination, liver and kidney function tests were observed. The treatment effects for dampens and sprains were also much better （P 〈 0.05 ）. Conclusion Shangkesan has more significant effect, through promoting blood circulation and removing blood stasis ,lessening swelling and pain, and more safety than 701 paste.
出处
《医药导报》
CAS
2008年第6期655-658,共4页
Herald of Medicine
基金
肇庆市科技局科技创新项目(2004年)(基金编号:104E501)
关键词
伤科散
软组织损伤
急性
Shangkesan
Acute injury in parenchyma
