摘要
目的:评价以利多卡因前列腺周围神经阻滞在经直肠超声引导前列腺穿刺活检操作中的止痛效果。方法:将120例符合经直肠前列腺穿刺指征患者随机分为三组,每组40例,分别接受2%利多卡因前列腺周围神经阻滞(阻滞组)和2%利多卡因凝胶20ml经直肠灌入(灌肠组),并设空白对照(对照组)。采用10针系统前列腺穿刺,穿刺后立即由专人询问患者的疼痛程度,并记录在10cm视觉模拟评分尺上。结果:阻滞组较灌肠组及对照组疼痛明显减轻(P<0.01),灌肠组与对照组相比疼痛似有减轻,但差异无统计学意义。结论:利多卡因前列腺周围神经阻滞,在经直肠超声引导前列腺穿刺活检操作中有较好的止痛效果。
Objective：To evaluate the local analgesia efficacy of periprostatic nerve block for transrectal ultrasound guided biopsy of the prostate. Methods： The study group comprised 120 consecutive men （median age 68 years） undergoing prostatic biopsy because of either an abnormality of prostate specific antigen （PSA） levels an or digital rectal examinition. They were randomized into three groups; Group 1 （40 cases） received 10 ml of 2% lidocaine infiltrated into the periprostatic nerve plexus bilaterally; Group 2 （40 cases） received 20 ml of 2% lignocaine gel rectally; Group 3 （40 cases） were recruited as controls. Systematic tenfold prostatic biopsy was taken in all cases. Immediately after the procedure patients were asked to indicate the degree of pain on a 10 cm visual analogue scale （VAS）. Results：Group 1 had significally less pain than the others （ P 〈0.01 ）. The rectal instillation of 2% lignocaine gel did not reduce pain significantly compared with the controls. Conclusions： A periprostatic nerve block with 2 % lidocaine was associated with significantly less pain during prostatic biopsy than was rectal lidocains gel or control.
出处
《临床泌尿外科杂志》
2008年第4期258-259,262,共3页
Journal of Clinical Urology
