摘要
目的探讨应用实时三维超声心动图对二尖瓣环立体几何参数测量的方法和准确性。方法采用实时三维超声心动图对9只健康杂种犬心脏在活体状态下进行检查，获取三维全容积数据库，应用TomTec三维分析软件与MATLAB软件对二尖瓣环进行标识和测量。测量参数包括：①瓣环前外侧连合（anterior commissure，AC）与后内侧连合（posterior commissure，PC）间距离（commissure-commissure，CC）；②通过瓣环前外侧连合与后内侧连合间连线中点并与之正交的室间隔侧和外侧瓣环间距离（septallateral，SL）；③瓣环高度（height，H）。二尖瓣环各参数的三维超声测值与离体心脏解剖测值进行比较。结果①CC，SL和H三维超声测值与离体心脏解剖测值的相关系数分别为r=0．83（P〈0．01），r=0．78（P〈0．05）和r=0．75（P〈0．05）。②Bland—Altman分析示三维超声测值与离体心脏解剖测值一致性良好，CC，SL和H测值的均数差分别为0．22cm，0．12cm和-0．08cm。结论实时三维超声心动图能够较好地显示二尖瓣环立体形态，并能进行准确的空间几何测量，为二尖瓣环的定量研究提供了一种简便、可靠、无创的方法。
Objective To validate the accuracy of real-time three-dimensional echocardiography（RT- 3DE） in measuring spatial geometric parameters of mitral annulus. Methods Hearts in vivo of nine healthy hybrid canines were examined by RT-3DE. Three-dimensional full-volume images of mitral annuli were acquired. The annuli were annotated and measured by TomTec 4D MV-assessment software and MATLAB. The distance between anterolateral and posteromedial commissure （commissure-commissure, CC）, septolateral distance（septal-lateral, SL） and height （H） of mitral annulus were measured. Parameters derived by RT-3DE were compared with anatomic measurements of the ex vivo hearts. Results O The correlation coefficients of CC,SL and H derived by two methods were 0.83（ P 〈0.01 ） ,0.78（ P 〈0. 05） and 0.75（ P 〈0.05） respectively.②Bland-Altman analysis demonstrated that RT-3DE measurements were well consistent with anatomic measurements,the mean differences of CC, SL and H between two methods were 0.22 cm,0.12 cm and - 0.08 cm respectively. Conclusions RT-3DE is feasible in measuring mitral annulus, which provided a convenient, accurate and reliable new method for quantitative assessing annulus geometry configuration.
出处
《中华超声影像学杂志》
CSCD
2008年第5期442-445,共4页
Chinese Journal of Ultrasonography
