摘要
目的探讨血清铁与高血压是否存在关联,为高血压病因研究奠定基础。方法以黑龙江报社人群为调查对象,于2005年7月对该人群进行高血压横断面调查,测量血压、身高、体重、腰围、臀围并进行生活方式相关因素的调查。现场采集空腹静脉血,检测血脂、空腹血糖、血清铁等指标。统计分析采用SAS 9.1.3统计软件,计算相应指标在高血压组和对照组人群中的差异。结果年龄、性别在高血压组与非高血压组差异均有统计学意义(P<0.01),2组的吸烟率和饮酒率差异无统计学意义(P>0.05)。高血压组的甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白(LDL)水平均高于非高血压组(P<0.01),高血压组的高密度脂蛋白(HDL)水平低于非高血压组(P<0.05);高血压组体质指数(BMI)和腰臀比(WHR)均高于非高血压组(P<0.01)。高血压组空腹血糖高于非高血压组(P<0.01)。单因素分析显示,低水平血清铁与原发性高血压有关(P<0.05),可能是保护因素(P>0.05),血清铁增加不会增加患高血压的危险。用Logistic回归分析调整年龄、性别、饮酒、甘油三酯、低密度脂蛋白胆固醇(LDL-C)、空腹血糖、BMI混杂因素后,血清铁与高血压的关联程度差异无统计学意义(P>0.05)。结论血清铁与原发性高血压无关联。
To explore the relationship between hypertension and serum iron in population of Heilongjiang Newspaper Office and to lay a foundation for hypertension etiological study. Methods The population of Heilongjiang Newspaper Office were selected as subjects to conduct the cross - sectional study in July 2005. All subjects were interviewed with questionnaire and measured for blood pressure, stature, weight, waist circumference, hip circumference and risk factors of life style. Blood specimens were collected for detecting serum lipid, fasting plasma glucose, serum iron . All data were analyzed with SAS 9.1 software. Results There was significant difference for age and gender between the hypertensives and normotensives （ P 〈 0.01）. The proportions of alcohol drinking and smoking had no significant difference in two groups. The average levels of TG, TC, LDL - c in hypertensives were higher than those in normotensives, but it was lower for HDL - c. Both the body mass index （BMI） and ratio of waist to hip circumference （WHR） were significantly higher in hypertensives than those in normotensives （ P 〈 0.01 ）. The level of fasting plasma glucose （FPG） was higher in hypertensives than those in normotensives. Data from monovariate analysis showed serum iron was related to essential hypertension （P 〈 0.05）, low level of serum iron might be a protective factor for them. The higher level of serum iron was not related with higher prevalence of hypertension. The prevalence of hypertension was not increased with the higher level of serum iron after adjusting by confounding factors. Conclusion Serum iron was not associated with essential hypertension.
出处
《中国公共卫生》
CAS
CSCD
北大核心
2008年第5期555-557,共3页
Chinese Journal of Public Health
基金
黑龙江省自然科学基金项目(D200623)
关键词
原发性高血压
横断面研究
血清铁
essential hypertension
serum iron
cross - sectional study
