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等效剂量的舒芬太尼和芬太尼在硬膜外分娩镇痛中的临床观察 被引量:2

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摘要 目的:比较等效剂量的舒芬太尼与芬太尼用于分娩镇痛的效果。方法:随机选择90例ASAⅠ-Ⅱ级、单胎、头位、足月妊娠的初产妇分成舒芬太尼组(S组)、芬太尼组(F组)和对照组(C组),每组30例。S组接受0.1%的罗哌卡因+0.4μg/m l的舒芬太尼,F组接受0.1%的罗哌卡因+2μg/m l的芬太尼,C组不使用任何镇痛药。S组和F组的产妇进入活跃期即宫口开至2-3 cm时进行硬膜外穿刺(L 3-4),向头端置管。注入镇痛液15 m l,观察它们的镇痛起效时间、维持时间及三组的镇痛效果、产程时间、新生儿情况及副作用。结果:镇痛组间产程及副作用无显著性差异,而S组在用药后5 m in和15 m in的VAS评分及需要连接病人自控镇痛(PCA)泵的时间与F组比较有显著性差异。分娩方式及对新生儿的影响三组间差异无显著性。结论:舒芬太尼与芬太尼用于硬膜外分娩镇痛效果确切,与芬太尼比较,舒芬太尼起效快,镇痛作用强,维持时间长。
出处 《中国妇幼保健》 CAS 北大核心 2007年第8期1033-1034,共2页 Maternal and Child Health Care of China
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