摘要
目的探讨湿疹样乳腺癌的临床特点,诊治方法及预后。方法回顾性分析作者在韩国首尔峨山医院进修时收集的85例湿疹样乳腺癌患者的临床资料。结果女性83例,男性2例。乳腺有湿疹样表现79例(92.9%),伴乳腺肿块52例(61.2%),其中同侧腋窝淋巴结转移27例(占本组85例的31.8%及占伴乳腺肿块病例的51.9%)。52例行乳癌改良根治术,30例行乳腺单纯切除术,3例行局部切除术。单纯乳头及乳晕湿疹样乳腺癌11例(12.9%),均为无乳腺肿块的病例,其余74例(87.1%)均合并其他类型的乳腺癌。本组5年生存率为82.1%,其中无乳腺肿块者5年生存率为93.9%,合并肿块者5年生存率为75.0%(P<0.05),无同侧腋窝淋巴结转移者5年率为96.6%,有转移者5年生存率为51.9%(P<0.01)。结论湿疹样乳腺癌有特殊的临床表现,但易误诊,病灶细胞学和病理学检查可以确诊,伴乳腺肿块者应选择乳癌改良根治术,无乳腺肿块者可选择乳腺单纯切除术,预后与乳腺肿块及同侧腋窝淋巴结转移密切相关。
Objective To investigate the clinical characteristics, diagnosis, treatment and prognostic factors of patients with eezematoid breast cancer. Methods The clinical data of 85 eczematoid breast cancer patients collected in Asan Hospital in Seoul of South Korea were retrospectively analyzed. Results There were 83 female cases and 2 male cases. Eczematoid lesions was observed in the breast of 79 patients (92.9%), breast lumps was observed in 52 patients (61.2%), homolateral axiUary lymph node metastasis was noticed in 27 patients ( accounted for 31.8% of 85 breast cancer cases and 51.9% of the patietns with breast lumps). Fifty cases were treated with modified radical mastectomy, 30 with simple mammectomy, 3 with partial mammectomy. The 5 - year survival rate of the breast cancer patients was 82.1%, the 5 - year survival rate of the those without breast lumps was 93.9%, and the 5 - year survival rate of the cases with breast lumps was 75.0% ,showing significant differences ( P 〈 0.05 ). While the 5 - year survival rate of the cases without homolateral axiUary lymph node metastasis was 96.6%, and 51.9% for those with homolateral axiUary lymph node meatstasis, also showing significant statistical differences (P 〈 0.01 ). Conclusion The clinical manifestations of eczematoid breast cancer is special but there might be misdiagnosis. Diagnosis of the disease can be confirmed by cytological and pathological exmiantion. Modified radical mastectomy is indicated for treatment of patients with breast lumps. Simple mastectomy can be used in treatment of those without breast lumps and the prognosis is associated with and without breast lumps and lymphnode metastasis as well.
出处
《中国热带医学》
CAS
2008年第5期763-765,共3页
China Tropical Medicine
关键词
湿疹样乳腺癌
特殊乳腺癌
预后
Eczematoid mammary cancer
Special mammary cancer
Prognosis