摘要
目的探讨阿米卡星致过敏性休克的特点和转归，为临床安全用药提供参考。方法利用“中文期刊全文数据库”、“中文科技期刊全文数据库”和“万方数据医药信息镜像系统”对1994-2007年9月国内医药学期刊上发表的文献进行检索，共检索到阿米卡星致过敏性休克的患者29例，对患者资料进行整理归纳和分析讨论。结果29例患者中，男14例，女15例，年龄1．5—89．0岁；为常规剂量静脉滴注、肌肉注射，1例为膀胱冲洗；其中有6例患者为联合用药；过敏性休克在用药后40min内出现；治疗后有26例患者康复，3例死亡。结论应用阿米卡星时，要密切观察患者的反应，严密预防过敏性休克的发生，做到早发现、早抢救，以免贻误抢救时机。
Objective To research the characteristics and outcom of amikacin - induced anaphylactic shock, and to provide reference for safe clinical medication. Methods The literatures between January 1994 and September 2007 were searched for from ＂ Chinese Journal Full - text Database＂ ,＂ Chinese Science and Technology Journal Full - text Database＂ , and ＂ Wanfang Medicine Data China info＂, 29 cases with amikacin - induced anaphylactic shock were collected and analyzed. Results Of the 29 cases, 14 （48. 3 % ） were male, 15 （51.7% ） female, aged 1. 5 to 89 years; They were given intravenous injection or intramuscular injection or bladder washout （ 1 case）. Most of anaphylactic shock occurred within 10 minutes （59. 3% ） after administration, and 26 cases recovered （89. 7% ） and 3 cases died （ 10. 3% ）. Conclusion This paper provided reference for the safe medication of amikacin
出处
《中国全科医学》
CAS
CSCD
2008年第8期685-687,共3页
Chinese General Practice
