摘要
目的:观察乳增灵对乳腺增生症患者黄体期性激素的影响。方法:45例乳腺增生症患者为治疗组.15例乳腺正常的女性作为对照组。治疗组服用乳增灵(由柴胡、当归、白芍、白术、夏枯草、鹿角胶等组成),治疗3月。检测雌二醇(E_2)、孕酮(P)、泌乳素(PRL)、睾酮(T)的浓度。结果:45例患者治疗后,临床治愈6例,显效17例,有效18例,无效4例。治疗组治疗前E_2、P、PRL浓度显著高于对照组(P<0.05)。治疗组治疗后E_2、P、PRL浓度下降。与治疗前比较,差异有显著性意义(P<0.05),治疗组治疗后与对照组比较,PRL浓度仍高于对照组(P<0.05)。结论:乳增灵治疗乳腺增生症的临床作用机理在于降低黄体期E_2、P、PRL的水平,调节紊乱的内分泌。
Objective:To observe the effect of Rusengling on sexual hormones in luteal phase of mastoplasia patients.Methods:Forty - five mastoplasia patients in the treatment group received Rusengling (mainly composed of Radix Bupleuri,Radix Paeoniae Alba,Rhizoma Atractyiodis Macrocephalne.Spica Prunellae,Colla Comus Cervi,et al.),and 15 healthy women served as the control.The treatment lasted 3 months.After treatment,the serum levels of estrogen(E_2),progesterone (P),pro- lactin (PRL)and testosterone (T)were detected,Results:Of the 45 patients,6 were clinically cured.17 markedly effective,18 effective and 4 ineffective.Serum levels of E_2,P and PRL in the treatment group were higher than those in the control group before treatment (P<0.05).After treatment,serum levels of above indexes were decreased in the treatment group (P<0.05 compared with those before treat- ment),and the serum level was still higher than that in the control group (P<0.05). Conclusion :The therapeutic mechanism of Rusengling for the treatment of msetopla- sis is related with the increase of serum levels of E2,P and PRL in luteal phase.
出处
《新中医》
CAS
北大核心
2008年第5期31-32,共2页
New Chinese Medicine
基金
广东省中医药局科研立项课题(编号:1040155)
