摘要
用培养法和PCR法对100例淋球菌阳性患者混合感染并行药物敏感性研究,结果显示:Gc+Uu、Gc+Mh、Gc+Ct、Gc+Tv、Gc+Cd、Gc+Uc+Mh、Gc+Uu+Ct、Gc+Mh+Ct、Gc+Uv+Mh+Ct、Gc+Ct+Uu+Tv混合感染阳性率分别为35%、25%、19%、1%、3%、21%、13%、5%、3%、1%。男性淋病患者混合感染率与女性患者相比,差异无显著性(P>0.05)。淋球菌对8种抗菌药物的耐药率达5%~60%,其中安必仙、先锋霉素V、菌必治耐药率分别为36%、5%、11%;氟味酸、氧氟沙星、环丙沙星为41%、23%、5%;乙酸螺旋霉素、红霉素为60%和51%。我们认为本研究结果可为临床泌尿生殖道淋球菌感染病人提供诊断、治疗和预防依据。
Mixed infection and drug susceptibility were investigated in 100 patients with gonococcus infection by the methods of cultivation and polymerase chain reaction (PCR). The results showed that the rates of mixed infection with Gc + Uu、 Gc + Mh、 Gc + Ct、 Gc + Tv 、 Gc + Cd 、 Gc + Uu +Mh、Gc + Uu +Ct、Gc + Mh +Ct、 Gc + Uu + Mh +Ct 、Gc + Ct + Uu + Tv were 35 % 、 25 % 、 19 % `1 % 、 3 % 、 21 %、 13 % 、 5 %、 3 % 、 1 % respectively. No obvious sex difference was observed (P>0.05). The drug resistance of gonococcus to 8 antibacterial drugs was 5 %-60 %. The percentages ofresistant strain to different drugs were as follows: Ampicillin (36),Cefazolin (5), Rocephin (11),Norfloxacin (41), Ofloxacin (23), Ciprofloxacin (5), Acetyl spiramycin (60), Erythromycin (51).