摘要
目的:寻找一种陶瓷材料替代金属材料成为种植体核心材料。方法:实验于2007-03/06在沈阳药科大学药理实验室完成。将碳化硅材料加工成直径5mm,厚度1mm的圆片,共3片。将碳化硅试件放入试管中,试管中加入10mL生理盐水,取2个试管做对照组,阴性对照组:10mL生理盐水。阳性对照组:10mL蒸馏水。每个试管中加入稀释兔血0.2mL。按公式计算溶血百分率:溶血百分率=(碳化硅试件吸光度值-阴性对照吸光度值)/(阳性对照吸光度值-阴性对照吸光度值)×100%。结果:碳化硅试件的溶血率为1.04%,小于5%。结论:碳化硅种植材料不会引起生物的急性溶血。
AIM： To search one ceramic material instead of metal material to be used as the core implant material. METHODS： The experiment was carried out in the Pharmacological Laboratory of Shenyang Pharmaceutical University between March and June in 2007. The SiC material was fashioned into three wafers of 5 mm diameter and 1 mm thickness. Then the material was put separately in the cuvette with l0 mL physiological saline solution as the test group, while those in the cuvette with l0 mL distilled water or l0 mL physiological solution were taken as the positive control group and the negative control group. The dilute rabbit blood （0.2 mL） was added into each cuvette. Haemolysis rate was measured according to the formula of （the absorbance value of SiC material-the absorbance value of negative control group）/（the absorbance value of positive control group-the absorbance value of negative control group）× 100%.
RESULTS： Haemolysis rate of the SiC implant material was 1.04%, which was lower than 5%.
CONCLUSION： The SiC implant material will not induce acute haemolysis.
出处
《中国组织工程研究与临床康复》
CAS
CSCD
北大核心
2008年第10期1873-1875,共3页
Journal of Clinical Rehabilitative Tissue Engineering Research
