摘要
目的：研究儿童胃幽门螺杆菌（ＨＰ）感染的特点，以及与上胃肠病的关系。方法：对１５３例因胃肠症状接受胃镜检查的有连续症状的患儿进行前瞻性、活检组织学、血清学、尿素酶法检查、并与２６５例成年患者及１８１例无症状健康儿童对照。结果：患儿ＨＰ感染率２９％，低于成年患者７１％（Ｐ＜００５），与健康儿童（３４％）无差异（Ｐ＞００５）。儿童消化性溃疡ＨＰ感染６８％，高于非溃疡组２２％（Ｐ＜００５），但显著低于成人组９８％（Ｐ＜００５）。ＨＰ相关胃炎儿童内镜无特征、组织学炎症细胞浸润活动明显。结论：儿童ＨＰ感染是溃疡致病因素，但非唯一因素，ＨＰ感染和症状无关，ＨＰ相关胃炎有一定组织学特点。
ims: To investigate the characteristics of Helicobacter pylori (Hp) infection in children and its relationship to upper gastrointestinal diseases. Methods: To study prospectively 153 consecutive symptomatic children undergoing gastroscopy by histology, serology, urease testing for Hp infection. The data of 265 symptomatic adults and 181 healthy children were used as control. Results: The rate of Hp infection in study group (29%) was lower significantly than that (71%) of adults (P<0.05), but no different from that (34%) of healthy children (P>0.05). The rate of Hp infection in peptic ulcer disease (68%) was significantly higher than that (22%) of nonulcer dyspepsia (P<0.05), but lower than that (98%) of adults (P<0.05). No endoscopic characteristics were found in Hp associated gastritis. Histologically inflammative cell infiltration and activity was obvious. Conclusions: Hp infection is an important, but not only, factor in the pathogensis of peptic ulcer in children. There is no relation between Hp infcetion and symptoms. Hp associated gastritis has same histological characteristics.
出处
《胃肠病学和肝病学杂志》
CAS
1997年第2期141-144,共4页
Chinese Journal of Gastroenterology and Hepatology
关键词
幽门螺杆菌
胃炎
消化不良
儿童
溃疡病
Helicobacter pylori peptic ulcer gastritis dyspepsia children.
