摘要
目的探讨肥厚型心肌病合并冠心病的发生率及临床意义。方法对1998年至2006年在我院接受冠状动脉造影118例肥厚型心肌病的患者发病情况、临床表现、辅助检测、诊断及预后等方面进行详细研究。结果有20例(17%)合并存在冠心病,冠心病组年龄高于非冠心病组(63±10vs51±17岁,P<0.05),冠心病组出现严重心绞痛发生率较非冠心病组为高(50%vs29%,P<0.05),随访期间,心源性死亡发生率,冠心病组高于非冠心病组(30%vs11.2%,P<0.05)。结论肥厚型心肌病患者中有较高的冠心病的发生率,45岁以上的肥厚型心肌病患者出现胸痛时,应行冠状动脉造影检查。合并冠心病者预后较差,应积极治疗。
Purpose To study the clinical significance of coronary artery disease （CAD） in hypertrophic cardiomyopathy （HCM）. Methods Coronary angiography was undertaken in 118 patients with HCM in our institute during 1998 to 2006, and the clinical characteristics of the patients were evaluated. Results CAD was recognized in twenty patients （17%） by coronary angiography. Compared with HCM patients without CAD, those with CAD were older （63 ± 10 vs 51 ± 17 years,P〈0.05）. Patients with CAD had more severe chest pain than those without CAD （50% vs 29%, P〈0.05）. The incidence of cardiac death in patients with CAD was higher than that in those without CAD （30% vs 11.2%, P〈0.05）. Conclusions The incidence of CAD in HCM is high. Coronary angiography should he undertaken in patients with HCM who are over 45 years old and have chest pain. Patients with HCM and CAD should he treated intensively due to poor prognosis.
出处
《复旦学报（医学版）》
CAS
CSCD
北大核心
2007年第5期706-708,713,共4页
Fudan University Journal of Medical Sciences
关键词
肥厚型心肌病
冠心病
冠状动脉造影术
hypertrophic cardiomyopathy
coronary artery disease
coronary angiography
