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心肌损伤标志物在不稳定型心绞痛中的应用价值 被引量:10

Application Value of Myocardial Damage Markers in Unstable Angina Pectors
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摘要 目的探讨肌红蛋白(MYO)、肌钙蛋白I(cTnI)、肌酸激酶同工酶(CK-MB)检测在不稳定型心绞痛(UAP)诊断中的应用价值。方法应用快速免疫层析法定性检测UAP患者入院即刻血清中的MYO、cTnI、CK-MB并计算其阳性率。结果45例UAP组中MYO阳性21例,阳性率46.67%;cTnI阳性9例,阳性率20%;CK-MB阳性4例,阳性率8.89%。与40例健康对照组相比较,UAP组中MYO和cTnI明显高于健康对照组(P<0.01),有明显统计学意义;而CK-MB与健康对照组比较差异无统计学意义(P>0.05),同时发现cTnI阳性的病人心肌梗死等复合心脏事件的发生率明显高于cTnI阴性者。结论MYO和cTnI在UAP诊断中有较高的临床应用价值。 Objective To explore the clinical value of myoglobin (MYO),cardiac tropinin I and CK-MB in the early diagnosis of unstable angina pectoris(UAP).Method MYO,cTnI and CK-MB in patients with UAP were measured by using quick immunochromatograply and the positive rate was counted.Results The positive rate of MYO was 46.67%(21/45),cTnI was 20%(9/45),CK-MB was 8.89%(4/45) in 45 patients of UAP. MYO and cTnI in UAP group were significantly higher than those in 40 cases of healthy controls (P〈 0.01).CK-MB in UAP group was not different from that in control group(P〉0.05).The incidence of composite endpoints in the positive group was significantly higher than that in negative group.Conclusions Detection of MYO and cTnI is of clinical values for the diagnosis of UAP.
出处 《现代诊断与治疗》 CAS 2008年第2期76-78,共3页 Modern Diagnosis and Treatment
关键词 不稳定型心绞痛 肌红蛋白 肌钙蛋白I 肌酸激酶同工酶 Unstable angina pectoris Myoglobin Cardiac tropinin I CK-MB
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  • 1叶任高,陆再英.内科学[M].第6版.北京:人民卫生出版社,2006.2,273. 被引量:1

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