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超重和肥胖人群血清脂联素水平与心血管多重危险因素的关系

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摘要 选取32例超重和肥胖者(OW+Ob组)和36例正常体重者(NC组),常规测量身高等,测定APN、甘油三酯(TG)、胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)等指标。结果:(1)OW+Ob组血清APN水平明显低于NC组(P<0.05);OW+Ob组WC、SBP、DBP、FINS、FBG、TG、TC、LDL-C、IL-6、hs-CRP均高于NC组(0.000<P<0.05);OW+Ob组ISI低于NC组,HOMA-IR高于NC组。(2)APN与BMI、WC、FINS、TG、TC、LDL-C、HOMA-IR、hs-CRP呈显著负相关(0.05>P>0.001);与HDL-C呈显著正相关(P<0.05)。(3)OW+Ob组女性血清APN水平较男性明显升高(P<0.05),APN与T,OW+Ob组人群中血清APN与T及T/E2均呈显著负相关(P<0.05)。(4)HDL-C是影响血清APN水平的独立相关因素。结论:超重和肥胖者血清APN水平明显降低,低APN水平与心血管多重危险因素密切相关。
作者 张杰 梁琳琅
出处 《实用糖尿病杂志》 2008年第2期25-27,共3页 Journal of Practical Diabetology
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参考文献11

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