摘要
目的:观察柔木丹颗粒治疗气虚血瘀瘀毒型慢性乙型肝炎的临床疗效,长期治疗的安全性。方法:选择气虚血瘀瘀毒型慢性乙型肝炎78例,随机分为两组,治疗组(40例)予柔木丹颗粒冲服,对照组(38例)予复方鳖甲软肝片口服。结果:治疗组总有效率为80%,治疗组乏力、腹胀、食欲不振、面色晦暗等症状、体征的改善较为明显;肝功能治疗前后比较,治疗组可显著降低血清ALT、AST、TBIL;治疗后,治疗组与对照组HA、LN、PCⅢ、CⅣ均显著下降,但两组比较差异无统计学意义(P>0.05)。
Objective ：To observe the clinical effect of the Roumudan Keli in treating chronic hepatitis B with Qi asthenia blood stasis and toxic retention ,the security of the long - term treatment. And to explore its mechanism of action preliminary. Methods ：78 Patients of chronic hepatitis B with Qi asthenia blood stasis and toxic retention were randomly divided into the treated group（40 cases） ,control group（38 cases） ,treated with the Roumudan Keli,FFBJRGP respectively, with half a year course, to observe the items of clinical symptoms, physical signs, hepatic function, and the serum fibrosis indices. Result ：The results showed that the total effective rate was 80% in the treated group after treatment ,clinical symptoms and physical signs, as follows debilitation,abdominal distention,anepithymia, dim complexion etc,were improved markedly in the treated group;Preand post - treatment the indices of hepatic function were compared, the level of the serums ALT,AST,TBIL of the treated group decreased obviously; After treatment, HA, LN, PC Ⅲ, IV C of the treated group and the control group decreased significantly, however there was no statistical significance between them （ P 〉 0.05 ）. Conclusion ： To the patients of chronic hepatitis B with Qi asthenia blood stasis and toxic retention ,there is alike curative effect on Roumudan Keli therapy and FFBJRGP therapy in resisting hepatic fibrogenesis. Roumudan Keli possess the function of protecting the hepatic ceils. And the function of ameliorating clinical symptoms and physical signs of the Roumudan Keli therapy are better than the FFBJRGP therapy.
出处
《辽宁中医杂志》
CAS
北大核心
2008年第4期539-540,共2页
Liaoning Journal of Traditional Chinese Medicine
