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非体外循环冠状动脉旁路移植术中血液回输与炎症反应的关系 被引量:2

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摘要 细胞因子介导了心脏手术后的炎症反应,并对器官功能衰竭的发生发展起重要作用,决定着患者的临床表现和转归。有研究表明,非体外循环冠状动脉旁路移植术(OPCABG)与体外循环(CPB)下冠状动脉旁路移植术(CABG)相比,细胞因子水平低,可减轻炎症反应;也有研究认为OPCABG与CPB下CABG细胞因子水平没有差别。研究表明,CPB所导致的全身炎症反应与血液和人工材料表面的接触所导致的单核/巨噬细胞活化及细胞因子释放有密切关系。OPCABG中血液回输与CPB有着相似的过程,有可能是影响OPCABG后细胞因子水平的一个因素。本研究目的在于研究OPCABG术中血液回输与术后炎症反应的关系。
出处 《中国危重病急救医学》 CAS CSCD 北大核心 2008年第4期234-235,共2页 Chinese Critical Care Medicine
基金 天津市自然科学基金资助项目(043613011) 天津市科技发展计划基金资助项目(05YFSZSF02700) 天津市医药卫生熏点基金资助项目(04KY03)
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