1Liu B, Jiang JW, Du WB, et al. Systemic infusion of naloxone reduces degeneration of rat substantia nigral dopaminergie neurons induced by intranigral injection of Lipopolysaccharide [ J ]. J Phannacol Exp Ther ,2000,295 : 125-132. 被引量：1
2Wu DC,Jacksen-Lewis V,Vila M,et al. Blockade of microglial activation is neuroprotective in the 1 -methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease[J]. J Neurosci,2002, 22 (5) :1763-1771. 被引量：1
3He Y, Appel S, Le W. Minocycline inhibits microglial activation and protects nigral cells after 6-hydroxydopamine injection into mouse striatum[J]. Brain Res,2001,909(1-2) :187-193. 被引量：1
4Liu B,Gao HM,Wang JY,et al. Role of nitric oxide in inflammationmediated neurodegeneration[ J]. Ann N Y Acad Sci ,2002,962:318- 331. 被引量：1
5Gao HM, Liu B ,Zhang W, et al. Novel anti-inflammatory therapy for Parkinson' s disease[ J ]. Trends Pharmacol Sci, 2003,24 ( 8 ) : 395- 401. 被引量：1
6Block ML, Hong JS. Microglia and inflammation-mediated neurode- generation:multiple triggers with a common mechanism[ J]. Prog Neurobiol,2005,76(2) :77-98. 被引量：1
7Pawate S, Shen Q, Fan F, et al. Redox regulation of glial inflammatory response to lipopolysaccharide and interferongamma [ J ]. J Neurosci Res ,2004,77(4) :540-551. 被引量：1
8Kim SU,de Vellis J. Microglia in health and disease[J]. J Neurosci Res,2005,81 (3) :302-313. 被引量：1
9Li G, Cui G, Tzeng NS, et al. Femtomolar concentrations of dextromethorphan protect mesencephalic dopaminergic neurons from inflammatory damage[J]. FASEB J,2005,19(6) :489-496. 被引量：1
10Zhang W, Shin E J, Wang T, et al. 3-Hydroxymorphinan, a metabolite of dextromethorphan, protects nigrostriatal pathway against MPTP-elicited damage both in vivo and in vitro[J]. FASEB J,2006,20 (14) :2496-2511. 被引量：1
2Ouchi Y,Vagi S,Yokokura M,et al.Neuroinflammation in the living brain of Parkinson' s disease.Parkinsonism Relat Disord,2009,15:200-204. 被引量：1
3Tansey MG,Goldberg MS.Neuroinflammation in Parkinson' s disease:its role in neuronal death and implications for therapeutic intervention.Neurobiol Dis,2010,37:510-518. 被引量：1
5von Bernhardi R,Tichauer JE,Eugenín J.Aging-dependent changes of microglial cells and their relevance for neurodegenerative disorders.J Neurochem,2010,112:1099-1114. 被引量：1
6Beach TG,Sue LI,Walker DG,et al.Marked microglial reaction in normal aging human substantia nigra:correlation with extraneuronal neuromelanin pigment deposits.Acta Neuropathol,2007,114:419-424. 被引量：1
7Luo XG,Ding JQ,Chen SD,et al.Microglia in the aging brain:relevance to neurodegeneration.Mol Neurodegener,2010,5:12. 被引量：1
8Miller KR,Streit WJ.The effects of aging,injury and disease on microglial function; a case for cellular senescence.Neuron Glia Biol,2007,3:245-253. 被引量：1
9Zhang F,Qian L,Flood PM,et al.Inhibition of IkappaB kinasebeta protects dopamine neurons against lipopolysaccharide-induced neurotoxicity.J Pharmacol Exp Ther,2010,333:822-833. 被引量：1
10Zhang W,Dallas S,Zhang D,et al.Microglial PHOX and Mac-1 are essential to the enhanced dopaminergic neurodegeneration elicited by A30P and A53T mutant alpha-synuclein.Glia,2007,55:1178-1188. 被引量：1
