摘要
目的:探讨血管周上皮样细胞分化肿瘤的临床病理特点及免疫表型。方法:对1例结肠血管周上皮样细胞分化肿瘤的临床病理和免疫组织化学进行分析、并结合相关文献复习,结果:肿块界限清楚,无包膜,镜下观察:瘤细胞包括上皮样细胞及梭形细胞,胞质丰富透明或呈颗粒状嗜酸性胞质,核分裂象少见,间质富于薄壁毛细血管,偶见管壁透明变的大血管。免疫表型肿瘤细胞HMB45和α-SMA阳性,而CD34、CD31、S-100、CK均阴性。结论:血管周上皮样细胞分化肿瘤是一组非常少见的间叶源性肿瘤,因其特殊形态、免疫组化表达应归入血管周上皮样细胞相关肿瘤,极少数可以是恶性.
Objective： To explore the pathological characteristics and immunophenotype of perivascular neoplasms with epithelioid cell differentiation of colon. Methods： 1 case of perivascular neoplasms with epithelioid cell differentiation of colon was confirmed, whose clinical pathological features and immunohistochemistry were analyzed and reviewed combining with relative literature. Results： The tumor was relatively well circumscribed. Microscopic findings： The tumor in an immediate perivascular location was epithelioid and spindle cells; resembling smooth muscle were seen away from vessels. The cells had a clear cytoplasm and oncocytic change. Thin capillary were seen rich in stoma areas. The tumor cells were positive for HMB45 but negative for CD34,CD31,S-100 and CK. Conclusion： The perivascular neoplasms with epithelioid cell differentiation are rare mesenchymal tumors,which are classified perivascular epithelioid cell correlated tumor because of their special morphology, and the malignant rarely appear.
出处
《现代生物医学进展》
CAS
2008年第4期689-690,F0003,共3页
Progress in Modern Biomedicine
关键词
结肠
血管周肿瘤
上皮样细胞分化
病理学
Colon
Perivascular Neoplasms
Epithelioid cell differentiation
Pathology
